Naphthalenones from a Perenniporia sp Inhabiting the Larva of a Phytophagous Weevil, Euops chinesis

Publication Type:Journal Article
:2012
Authors:Y. Feng, Wang, L., Niu, S., Li, L., Si, Y., Liu, X., Che, Y.
Journal:Journal of Natural Products
Volume:75
Pagination:1339-1345
Date Published:Jul
:0163-3864
:Euops chinesis
:

The new naphthalenone derivatives perenniporides A-D (1-4) were isolated from solid cultures of a fungus Perenniporia sp. inhabiting the larva of Euops chinesis, a phytophagous weevil with high host specificity to the medicinal plant Fallopia japonica. The structures of 1-4 were elucidated primarily by NMR experiments, and 1 was confirmed by X-ray crystallography. The absolute configuration of 1 and 2 was assigned by electronic circular dichroism (ECD) calculations, whereas that of the C-10 tertiary alcohol in 3 was deduced via the CD data of the in situ formed (Rh2(OCOCF3)4) complex and supported by the ECD data Compound 1 showed antifungal activity against five plant pathogens.

Scratchpads developed and conceived by (alphabetical): Ed Baker, Katherine Bouton Alice Heaton Dimitris Koureas, Laurence Livermore, Dave Roberts, Simon Rycroft, Ben Scott, Vince Smith